Mouth and oropharyngeal cancer





Types and grades

Most mouth and oropharyngeal cancers are squamous cell cancers. But there are less common types. Read about the different types and grades. 

Squamous cell cancers of the mouth and oropharynx

More than 90 out of 100 (90%) mouth and oropharyngeal cancers are squamous cell carcinomas. Squamous cells are the flat, skin like cells covering the inside of the mouth, nose, larynx and throat. Carcinoma means cancer. Squamous cell carcinoma is cancer starting in the squamous cells.
Verrucous carcinoma is an unusual type of squamous cell carcinoma. It spreads to other parts of the body but can grow very deeply into surrounding tissues.  

Other types of mouth and oropharyngeal cancer

About 10 out of 100 (10%) mouth and oropharyngeal cancers are one of the following types. 
Salivary gland cancer 
There are minor salivary glands throughout the lining of the mouth and oropharynx. It is more common for a lump in this area to be non cancerous (benign). But cancers can develop in these glands. They are mostly a type of cancer called adenocarcinoma. Adenocarcinomas are type of cancer that start in glandular tissue.
Adenoid cystic tumour 
This is a rare type of tumour and can develop from glandular tissue in the salivary glands or the mouth. The parotid gland is the most common place to find this type of cancer. About 25 out of 100 (25%) tumours found in the parotid gland are cancer.

Symptoms

Read about the symptoms of mouth and oropharyngeal cancer and when to see your doctor.

Ulcers that do not heal

A broken area in the lining of the mouth (ulcer) that will not heal is a common symptom of mouth cancer.

Pain in your mouth

Pain or discomfort in your mouth that doesn't go away is the other most common symptom of mouth cancer. 

Red or white patches in the mouth or throat

An abnormal looking patch could be a sign of cancer or precancerous changes:
  • White patches are called leukoplakia.
  • Red patches are called erythroplakia. 
These patches are not cancer, but if left untreated they may lead to cancer. 
Red and white patches in the mouth can also be caused by a fungal infection called Thrush. The white patches usually rub off, leaving a sore red patch underneath. If you have anti fungal treatment, and the patches go away, they are not related to cancer. 

Difficulty swallowing

Mouth cancer can cause pain or a burning sensation when chewing and swallowing food. Or you might feel like your food is sticking in your throat. Difficulty swallowing can also be caused by a narrowing of the foodpipe (oesophagus). 

Speech problems

Cancer in your mouth or throat can affect your voice. Your voice might sound different. It may be quieter, husky, or sound as if you have a cold all the time. Or you might slur some of your words, or have trouble with pronouncing some sounds. 

A lump in your neck

You may have a lump in your neck caused by an enlarged lymph node. Swelling in one or more lymph nodes in the neck is a common symptom of mouth and orpharyngeal cancer. 
A hot red painful lump usually means an infection, rather than a cancer. Lumps that come and go are not usually due to cancer. Cancer usually forms a lump that slowly gets bigger. 

Weight loss

Weight loss is a common symptom of many different types of cancer. Mouth and oropharyngeal cancer can make it painful to eat and diffcult to swallow. This might cause weight loss. 
Extreme weight loss (when you are not dieting) can be a sign of advanced cancer. 

Bad breath

Most people have bad breath at some point in their life and it is not cancer. 
But if you have cancer, bad breath might be worse and happen more often. 

Other symptoms

These can  include one or more of the following:
  • a lump or thickening of your lip 
  • a lump in your mouth or throat 
  • unusual bleeding or numbness in your mouth 
  • loose teeth for no clear reason 
  • difficulty moving your jaw 
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